Formulation and Evaluation of Boswellia serrata Gel for Topical Pain Management

Abstract

The present study focuses on the formulation and evaluation of a topical herbal gel containing Boswellia serrata for effective pain management. Pain associated with conditions such as arthritis, muscle strain, and inflammation is commonly treated with synthetic drugs, which often produce adverse effects on long-term use. Hence, this study aims to develop a safer, natural, and cost-effective alternative using herbal ingredients. Boswellia serrata, known for its potent anti-inflammatory and analgesic properties due to boswellic acids, was selected as the primary active ingredient. The gel formulation also incorporated other herbal components such as curcumin, neem extract, menthol, and lavender oil to enhance therapeutic efficacy. The gel was prepared using Carbopol 940 as a gelling agent along with suitable excipients to ensure stability and patient acceptability. The formulated gel was evaluated for various physicochemical parameters including appearance, pH, viscosity, spreadability, homogeneity, washability, and skin irritation. The results indicated that the gel possessed a smooth texture, appropriate pH (5.2–6.1), good spreadability, and optimal viscosity, making it suitable for topical application. No signs of irritation were observed, confirming its safety. Additionally, the formulation demonstrated sustained drug release and significant anti-inflammatory activity, supporting its effectiveness in managing pain and inflammation. The study concludes that the developed Boswellia serrata gel is a promising herbal alternative to conventional analgesics, offering localized action with minimal side effects. Further clinical studies are recommended to validate its therapeutic potential and commercial applicability.